Epoxidation reaction

One of the oxidation reactions. Usually, an oxygen atom is introduced into an oxygen atom and a reaction of an oxygen atom is introduced to form a reaction of 1,2- * epoxy compound. There are mainly two forms: (1) indirect epoxidation: an alkene, which is made of halogenated alcohol, then reuse, or the like. (2) Direct epoxidation: 1 alkenylene air oxidation method: The low-grade olefin is oxidized with air gas in the presence of a catalyst. 2 alkene oxidation method: organic peroxide can be obtained by carboxylic acid and action. Ethylene and a certain amount of peroxide (0 ° C - room temperature) were carried out in anhydrous inert organic solvent () and in the presence of an acid catalyst (, a strong acid ion exchange resin). The improved method is to dissolve the alkene in glacial acetic acid (acetic acid), and then adding a small amount of acid catalyst to 60-70 ° C. The oxygen (vinegar) vinegar generated in the reaction system is for the reaction. This method is safer, called "in situ epoxidation method."

Some epoxides can cause carcinogene, such as epoxidated product epoxycene chloride, such as vinyl chloride, is carcinogene. The epoxide properties of some exogenous chemicals are extremely stable, which can stay in environmental and body adipose tissues, such as epoxidation of the organochlorine antibiotic Aira, has caused a serious ecological problem. Also, some chemicals are extremely unstable, and hydroxylation will continue to form a dihydrobiol compound. The epoxidation reaction can be divided into an aliphatic epoxidation reaction and an aromatic epoxidation reaction. The latter epoxidation product is unstable and will continue to occur.